Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms
Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms
Celphedia partners has developed comprehensive panel of phenotyping tests and customized genetic or environmental animal models to assess most biological functions or their pathologies. You can find the appropriate species for your project among Celphedia centers, and our scientific experts can help you to design the most relevant protocols for your project.
Successful long term collaborations with French and European partners and historical participation to European and international functional genomics programs (Fondation maladies rares, A.F.S.C.-C.F.C, Gencodys Consortium, IMPC consortium…) allowed generation of customed mouse models for rare diseases to investigate gene function and human pathophysiology.
Psychiatric disorders are behavioral, emotional, or cognitive dysfunctions that are not readily controlled by the individual and are related to clinically significant distress or impairment in one or more areas including social, occupational, and interpersonal functioning. The behavioral and emotional response is beyond a culturally expected response to common life stressors and losses.
Several procotols are implemented for evaluation of Anxiety-related behavior, susceptibility to despair -a symptom of Depression-, sensorimotor gating -altered in Schizophrenia-, or social behavior - a recognizable symptom of Autism Spectrum Disorder.
A wide range of neurological functions and their pathologies are explored both in rodents and primates, using multifunctional or specialized tests. Celphedia centers also developed specific genetic and environmental models to improve knowdege on pathophysiological mechanisms of neurological disorders and to screen for potential therapeutics.
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD are the primary cause of mortality over the world. Sveral models and tests are available to evaluate functional or anatomical abnormalities related to heart and vessels.