The platform of transgenesis, animal breeding and functional exploration Anexplo/GenoToul has numerous of equipments allowing the functional exploration and the phenotypic analysis (biological and histomorphological markers) of physiopathological animal models.

  • Creation of models by:
    • additive transgenesis
    • injection of ES cells
    • irradiation
    • transplant of organs or cells (microsurgery)
    • genetic crossings
  • Cryogenic preservation and decontamination of the transgenic lines
  • Imaging (gamma camera, echocardiography, intravital microscopy)
  • In vivo and ex vivo functional analyses
  • Producing, housing and breeding mutant lines in SPF conditions, experimentations within different confinement levels (1, 2 and 3)
  • Experimental protocols on rodents and mini-pigs

  • Training in Transgenesis, Cryogenic preservation, Microsurgery, experimental techniques (sample takings, anesthesia and surgery, Histology and Immunochemistry)
  • Master's degree of Bioengineering, Anatomopathology (of model animals) and Vectorology
  • Professional License of Physiopathology and Pharmacology of laboratory animals at Universities René Descartes (Lyon) and Joseph Fourier (Grenoble)
  • Training in biology and use of laboratory animals at Veterinary National School of Toulouse (level I and II)

Transgenesis, zootechny, cryoconservation and microsurgery

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Anexplo logoMouse, rat, hamsters and mini-pig

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