Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms

Ethics & animal welfare

Celphedia nodes work under European Directive 20120/063 EU and its French transposition (European Directive 2010/063 EU, French « Decree n° 2013-118 » about protection of animals used for scientific purposes).

Animals we work with are bred in our facilities or come from certified breeders.

Celphedia centers have official licenses delivered by the official regional vet (DDPP) to take care of animals, breed them and perform protocols. Housing conditions are standardized and match with the regulation to respect animal welfare.

Welfare responsibilities

Animal care and welfare is considered a responsibility of all staff, alongside compliance with legislation.

Professional technical staff who undertake the husbandry and care of our animals and have significant experience and knowledge of a range of species.

Specialised technical staff with specific expertise in surgery, performing functional protocols or monitoring disease models.

Ethical Review Committee and Animal Welfare Body (AWB)

All animal research at Celphedia centers is overseen by an Animal Welfare and Ethical Review Bodies

Ethical committee

Each research project using animals should have a project license prior conducting any experiment. Each Celphedia center have its proper Ethical committee or take part in regional one.  The principal investigator submits a project license application to the Ethical committee in which he/she details the research that will be carried out and justify the use of animals. in this regard, the CELPHEDIA WG3.3, dedicated to Ethics, published a Guide for writing the project licence application to help the researcher in this step.

The ethical committee members meet regularly to review scientific projects and provide Go/No Go decision to the ministry of agriculture who delivers the license to the principal investigator to carry the study. The review process involves critical evaluation of all ethical, scientific and welfare issues related to any research project.

Animal Welfare Body (AWB)

Its main missions are advising research teams, answer ethical and animal welfare issues, visit animal facilities to check the well going of protocols and develop an ethical way of working with animals in the long term.

The AWB together with the Ethical committee are reviewing retrospectively harmful project to follow up outcomes taking into account the effect on the animals used and to identify and advise on elements that could further contribute to the 3Rs for future projects.