Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms

Disease investigation

Celphedia partners has developed comprehensive panel of phenotyping tests and customized genetic or environmental animal models to assess most biological functions or their pathologies. You can find the appropriate species for your project among Celphedia centers, and our scientific experts can help you to design the most relevant protocols for your project.

Rare diseases

Successful long term collaborations with French and European partners and historical participation to European and international functional genomics programs (Fondation maladies rares,  A.F.S.C.-C.F.CGencodys Consortium, IMPC consortium…) allowed generation of customed mouse models for rare diseases to investigate gene function and human pathophysiology.

Psychiatric diseases

Psychiatric disorders are behavioral, emotional, or cognitive dysfunctions that are not readily controlled by the individual and are related to clinically significant distress or impairment in one or more areas including social, occupational, and interpersonal functioning. The behavioral and emotional response is beyond a culturally expected response to common life stressors and losses.

Several procotols are implemented for evaluation of Anxiety-related behavior, susceptibility to despair -a symptom of Depression-, sensorimotor gating -altered in Schizophrenia-, or social behavior - a recognizable symptom of Autism Spectrum Disorder.

Anxiety-related behavior
Susceptibility to despair/depression
Attention deficit hyperactivity disorder
Autism-spectrum disorders

Neurological diseases

A wide range of neurological functions and their pathologies are explored both in rodents and primates, using multifunctional or specialized tests. Celphedia centers also developed specific genetic and environmental models to improve knowdege on pathophysiological mechanisms of neurological disorders and to screen for potential therapeutics.

Skeletal and neuromuscular diseases/Parkinson's disease and ataxia
Learning and memory/Alzheimer's disease
Pain and proprioception
Sensory organs
Circadian rhythm/sleep disorders

Cardiovascular diseases

Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD are the primary cause of mortality over the world. Sveral models and tests are available to evaluate functional or anatomical abnormalities related to heart and vessels.

Cardiac hypertrohy
isoproterenol cardiac hypertension
Angiotensin II hypertension
DOCA-induced hypertension
L-NAME-induced hypertension
Salt-induced hypertension

Metabolic disorders

Diet-induced obesity
Energy inbalance

Immunology Inflammation & Infectious diseases

COVID19 mouse model
Bordetella pertussis infection model
Brucella abortus infection model
DSS-induced acute colitis
Experimental autoimmune encephalomyelitis model (EAE)
Neisseria meningitidis infection model
Neutropenia (Genista model)
Peritonitis inflammation model (Thiogl, LPS, plC)
Psoriasis (Imiquimod)
T cell induced inflammatory bowel disease (IBD) model

Respiratory diseases

HDM-induced asthma model
LPS-induced lung inflammation
Ovalbumin-induced asthma model
Elastase-induced lung emphysema
Bleomycin-induced lung fibrosis
Metacholine-induced bronchoconstriction
Pulmonary Arterial Hypertension (PAH)


Syngenic models, Xenographts
Orthotopic models
Genetic models in target organs
B16F10 melanoma tumor model
B16F10 -OVA melanoma tumor model