Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms

Model generation - personalized genome editing

Through Celphedia centers, the genetic engineering services developed sophisticated genetic tools to generate the relevantly customized model for your research. Our experts are flexible either to use your available vectors to generate the genetic model, or to design the most adapted vector construction to address your scientific question. Depending on the species studied, specialized Celphedia centers are provided by solid expertise to generate Mouse (PhenominAniRa, Anexplo, TEFOR TACGene), Rat (Phenomin, TRIP, TEFOR TACGene), Fly (TEFOR Fly Facility) , and Zebrafish (TEFOR TACGene, Anexplo) genetic models. Celphedia experts can also induce genetic modifications in different cell lines (TEFOR TACGene, Phenomin, TRIP) providing, whenever possible, alternative to use of animals in research in line with "Replace" aspect of the 3Rs


CRISPR/Cas9 Genome Editing
Tale nucleases
Homologous Recombination in ES cells
Transgenesis by pronuclear Injection
Viral Transduction
Structural variants
Rosa26 Targeting Overexpression
Flex models
Flp and Cre Deleters